Case-Control Study

Learning Objectives

A. Learn to apply the main features of case-control design :

  1. Formulate research hypotheses
  2. Define your source population and the eligibility criteria for cases and controls
  3. Define your exposure and outcome of interest
  4. Describe methods of accrual for cases and controls

B. Employ steps in data analysis of case-control studies to analyze the data:

  1. Calculate disease odds ratio
    • Interpret your estimate
  2. Calculate exposure odds ratio
    • Interpret your estimate
  3. Explain why exposure odds ratio is identical to the disease odds ratio

C. Explain your findings and discuss problems in data analysis:

  1. Discuss the principles of proper selection of cases and controls
  2. Discuss the relationship between odds ratio and risk ratio