Quiz 1, Module Randomized
1. Based on the facts presented, which do you think is the best hypothesis to study in this randomized trial?
- Individuals randomized to receive KimFaderol will be more likely to be cured of Susser Syndrome than will individuals randomized to placebo
- Individuals randomized to receive KimFaderol will have a lower risk of being diagnosed with Susser Syndrome than will individuals randomized to receive placebo
- Individuals with Stage I or II Susser Syndrome randomized to receive KimFaderol will be less likely to develop impaired proprioception than will individuals with Susser Syndrome randomized to receive placebo
Answer (a) —
incorrect:
Since KimFaderol is designed to prevent the onset of Stage III of Susser Syndrome (characterized by severely impaired proprioception), but does not claim to cure the disease, we would not expect KimFaderol treatment to lead to cure.
Answer (b) —
incorrect:
Everyone in this study has already been diagnosed with Stage I or Stage II Susser Syndrome.
Answer (c) —
correct:
This hypothesis specifies (1) the exposure groups (KimFaderol and placebo), (2) the outcome under study (impaired proprioception, (3) the population of interest (individuals diagnosed with Susser Syndrome but not yet experiencing impaired proprioception, and (4) the expected direction of effect.